Anderlecht vs 1899 Hoffenheim

Anderlecht have lost 13 of their last 19 meetings with German sides in all competitions (W3 D3), most recently a 2-1 home loss to Bayern Munich in the 2017-18 UEFA Champions League.

Hoffenheim have won both of their previous matches against Belgian opponents, winning 4-1 both home and away against KAA Gent in the 2020-21 UEFA Europa League group stage.

Including qualifiers, RSC Anderlecht are unbeaten in their last eight home games in European competition (W5 D3), their longest run since a run of nine from 2002 to 2004.

TSG Hoffenheim were winless in their first six away major European matches (D3 L3), then won two in a row, but are now winless in five (D3 L2).

TSG Hoffenheim must win this match to have any chance of qualifying for the knockout round play-offs. Should they fail to do so, they will be the first German club to be eliminated from the group stage/league phase of the UEFA Europa League since Borussia Mönchengladbach in 2019-20.