FC Twente’s only previous meetings with Italian opposition in the UEFA Cup/Europa League came in the 1974-75 UEFA Cup semi-finals, winning both legs versus Juventus before losing to Borussia Mönchengladbach in the final.
Lazio have lost each of their last three away games against Dutch opponents in European competition, all since the beginning of the 2022-23 season and in a different competition each time: 0-1 at Feyenoord in 2002-23 UEFA Cup, 1-2 at AZ in 2022-23 UEFA Conference League and 1-3 at Feyenoord in 2023-24 UEFA Champions League.
FC Twente are winless in their last nine UEFA Europa League matches (D6 L3), with both of their matches so far this season finishing 1-1.
Lazio have won both of their UEFA Europa League games this season – only in 1993-94 (UEFA Cup) and 2017-18 (Europa League) have they won their first three major European games in a single campaign.
Lazio have scored more goals than any other side in the UEFA Europa League this season (7), while only Elfsborg (33.3%) have a higher shot conversion rate than the Italian side (25.9%).